Common antibiotics, like amoxicillin, won’t change the effectiveness of nexplanon. The antibiotic rifampin (also known as Rifadin and Rimactane) is the only exception — it can lower the effectiveness of nexplanon and other birth control methods. Rifampin is an antibiotic used to treat tuberculosis.
Some other medicines can make nexplanon less effective. It’s important to let your nurse or doctor know about any drugs and medicines you take — prescription, overthecounter, recreational, vitamins, and herbal supplements — before they prescribe anything new for you.